The Sokoloski Lab at the University of Louisville School of Medicine and the Center for Predictive Medicine and Emerging Infectious Diseases (CPM) is seeking applications for a Postdoctoral Research Associate with an anticipated start date of Fall – Winter 2020.
The Sokoloski Lab's research interests focus on defining the mechanisms underlying the functional regulation of viral RNAs during infection. We use a number of RNA viruses as model pathogens, but have always had a fondness for members of the genus Alphavirus. As a result, much of the work we do pertains directly to alphavirus-induced arthritis. Our lab uses tissue culture based models of infection, robust in vitro systems, innovative discovery approaches, and small animal models of pathogenesis to characterize the molecular biology of BSL-2 and BSL-3 viral pathogens- from entry to exit.
Questions we seek to address are- i) How are the genomic RNAs of positive-sense RNA viruses able to efficiently interact with the host machinery upon entry to the cytoplasm; ii) How do viral RNAs alter their functions during viral infection to accomplish the needs of the lifecycle; iii) What host / pathogen interactions are essential for infection; and iv) What is the impact of these processes on the development of pathology?
Specific projects associated with this position will include the in vitro and in vivo assessments of noncapped viral RNA functions during alphaviral infection. Secondary roles in other Sokoloski Lab projects may fall within the purview of the position.
Examples of Duties-
• Design and conduct research activities relating to alphaviral molecular infection and pathogenesis using cellular and in vivo models of infection.
• Collect, prepare, and analyze research data, this includes keeping a detailed notebook and effective recordkeeping of datasets (both paper and electronic).
• Prepare manuscripts for publication to reputable journals; and prepare / deliver presentations to international, national, and regional research conferences.
• Stay current with the primary literature base and compiling / presenting pertinent scientific literature as needed.
• Supervise other personnel in the laboratory and coordinate research activities between the Sokoloski Lab, UofL research facilities, and other collaborative research groups.
• Participate as a mentor in the training of junior lab members, including research outreach trainees.
• Practice good lab and academic community citizenship and be an active contributor to the UofL Virology Supergroup.
To learn more about our research and meet our research group, please visit- www.SokoloskiLab.com
Interested?- Please send a complete CV, Unofficial Graduate Transcripts, Personal Statement, and a list of References to SokoloskiLabUofL@gmail.com
Equal Employment Opportunity- The University of Louisville is an equal opportunity, affirmative action employer, and is committed to providing employment opportunities to all qualified applicants without regard to race, sex, age, color, national origin, ethnicity, creed, religion, disability, genetic information, sexual orientation, gender, gender identity and expression, marital status, pregnancy, or veteran status.