The Infectious Diseases group at Moderna is seeking a talented, experienced and motivated Scientist with experience in virology, molecular biology, infection quantification assays, in vitro and in vivo study design and execution, and vaccine development. The Scientist will be part of teams responsible for advancing therapeutic and vaccine candidates from discovery through IND-enabling studies and clinical trials. The candidate will design, execute and interpret experiments to evaluate novel vaccines and antibody-based therapies for viral diseases. This work will include identifying vaccine targets and development and execution of studies to evaluate efficacy, immune responses, host-pathogen interactions, and protein characterization. In addition, the Scientist will help to identify, develop, and use novel screens to identify vaccine approaches that work best for targets of interest. He/she/they will interface with collaborators and present results both internally and externally. The ability to effectively communicate across internal multi-disciplinary teams and with external partners is required. Applicants should be outstanding scientists, collaborative team members, excellent communicators, and excited to work with cutting edge mRNA technology in the advancement of vaccines against viral pathogens.
Here's What You’ll Do:
Propagate, quantify, and qualify viruses
Design and conduct assays to determine virus infectivity and antiviral activity, including virus quantification and neutralization assays.
Manage and track data and inventories of virus, cells, samples, and key reagents.
Analyze, quality check and present complex data
Assist in the identification of new targets for vaccine intervention and/or identification of novel approaches that utilize the mRNA platform in the development of new or better vaccines.
Review literature for scientific evidence and advances related to viral infection, natural immunity, animal model and vaccine development.
Manage multiple experiments, projects and interactions with supporting functions simultaneously.
Here’s What You’ll Bring to the Table:
Ph.D. in virology, microbiology, or related discipline.
Publication of original scientific work in high-quality journals
Demonstrated ability to design and execute new experimental approaches
Excellent team spirit, communication and presentation skills
Strong expertise in virological assays such as viral culture, neutralization, and quantification assays.
Experience in cellular and molecular biology (e.g. cell culture, qPCR, transfections, transductions, western blotting, ELISA, flow cytometry).
Knowledge of immunology and host-pathogen interactions is a plus.
Ability to work in a cross-functional work environment
Candidate will be curious in exploring new path for drug discovery, bold in proposing creative experimental designs and ideas. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes