In Vivo Studies in Natural Host Resistance to HIV-1
Highly motivated, ambitious, driven and talented postdoctoral fellow are sought to join a research program that studies the block of HIV-1 replication by natural restriction factors. Our program has made important contributions to the mechanism used by TRIM5, CPSF6, MxB, SERINC5 and SAMHD1 to block HIV-1 infection. Recently, we have developed knockout mouse models for the different restriction factors and plan to investigate the role of these proteins in vivo. The individual is expected to join a fast pace moving environment. The laboratory is located in the new Price Center Building, a recently constructed state-of-the-art biomedical research facility centrally located on the campus of the Albert Einstein College of Medicine. Funding is currently available for up to 3 years, with the possibility of further extensions.
This program aims to gain immunological and cellular biological understanding of the mechanism by which different restriction factors block viruses in vivo: 1) recent PhD or MD/Ph.D degree, 2) experience in mouse immunology, 3) experience handling transgenic and knockout mice, 4) Multicolor flow cytometry, 4) viral or other pathogen challenge in mice. Applicants must have at least 1 paper in a peered reviewed journal. Please send a CV, and names for up to three references by email to Felipe Diaz- Griffero (email@example.com).
Diaz-Griffero Lab Websites: