The Research Institute Center for Vaccines and Immunity
An NIH-funded postdoctoral position is immediately available at The Ohio State University/ Nationwide Children’s Hospital to study the interaction of human innate immune cells with respiratory syncytial virus (RSV) infected, well differentiated human bronchial epithelial (HBE) cultures and alveolar organoids. Individual genes in these primary cultures will be knocked out or down using lentivirus vectors to determine their importance in RSV infection. Fluorescent protein expressing RSV enables real time tracking and can be further modified to study viral gene functions during infection of these ‘near in vivo’ cultures. The lab collaborates with clinical RSV experts at NCH and veterinary RSV experts at OSU. A major goal of all of our laboratories is to generate a highly effective live attenuated RSV vaccine that will protect children from severe RSV disease.
Responsibilities: The candidate must be highly motivated, have excellent technical and communication skills, perform self-directed research, and assist the PI in preparing manuscripts and grant applications.
Minimum requirements: Candidates must have a PhD or equivalent with strong research experience in molecular biology and cell biology. Applicants with experience in immunology or virology are particularly encouraged to apply. Salary will be competitive, commensurate with experience. Interested applicants should submit a CV, a brief description of their research achievements and interests, and a list of three references to Mark E. Peeples, PhD.