Tumor Virus Discovery Technologies

University of Pittsburgh

  • Post Doctoral Position - Academic
Job Type/Arrangement:
  • Full Time

We have developed new technologies to identify undiscovered human cancer viruses.   Our past work discovered KSHV/HHV8, the cause of Kaposi sarcoma,  and Merkel cell polyomavirus, the only polyomavirus causing human cancer.  Digital transcriptome subtraction (DTS) used to discover Merkel cell polyomavirus was the first use of a non-directed human sequencing pipline to identify a human viral pathogen.   In collaboration with the University of Pitt BioMS Center (http://www.bioms.pitt.edu/resources.html), which has a full suite of proteomic resources, we are evaluating a new initiative for virus discovery using proteomics.  It is anticipated that the applicant will be able to contribute to--and expand on--an established and working experimental procedure .  This project is supported by long-term R35 funding.  Successful candidates will have strong molecular biology skills, superior publication record and an appetite for creative yet rigorous research. Expertise with mass spectrometry, immunohistochemistry, UNIX-based bioinformatics, transcriptomics and proteomics are helpful though not required.   Willingness to learn these and other techniques is essential.  While a virology background is helpful, exceptional MD/PhD graduates with a strong research track record in other areas are welcome to apply.  

Please contact Patrick S. Moore (psm9@pitt.edu) and Yuan Chang (yc70@pitt.edu), Cancer Virology Program. Res Pav 1.8, University of Pittsburgh Cancer Institute, 5117 Centre Ave, Pittsburgh, PA 15213 http://www.tumorvirology.pitt.edu

Health insurance, Univ Pittsburgh Postdoc training and career development
Education Requirement:
MD or PhD
Years of Experience:
Required Skills & Areas of Study:
  • molecular virology
  • mass spectrometry
  • molecular cell biology
  • mammalian tissue culture
  • bioinformatics
  • cancer biology
  • transcriptomics
  • next gen sequencing
  • dna Viruses
  • rna viruses
External job URL:
$50,000 pa
University of Pittsburgh
Cancer Virology Program
5117 Centre Ave, Research Pavilion 1.8
Pittsburgh , PA 15213
Pat Moore, MD MPH