Characterization of novel RNA bacteriophages and bacterial immune responses

Washington University in St. Louis

Categories:
  • Post Doctoral Position - Academic
Job Type/Arrangement:
  • Full Time
Description:

Postdoctoral position is available in the lab of Dr. David Wang at Washington University in St. Louis. RNA bacteriophage have been largely ignored by the scientific community and little is known about their diversity or their impact on the microbiome.  Also, there are currently no known bacterial defense mechanisms against RNA viruses.  We have discovered 100s of novel RNA bacteriophage in virome studies (e.g. Krishnamurthy et al, PLOS Biology 2016). In addition, we hypothesize that a taxon of viruses commonly found in enteric viromes, the picobirnaviruses, are actually the 3rd known family of RNA bacteriophages ( Krishnamurthy et al, Virology 2018) rather than eukaryotic viruses. The foci of this position include identification of the bacterial hosts, culturing of novel RNA phage, defining the impact of RNA phage on the microbiome, and defining bacterial defense systems against RNA phage.  


 Please send CV and brief statement of interests to davewang@wustl.edu.

Education Requirement:
Ph.D. or equivalent in Virology, Biochemistry, Molecular Biology or related fields
Required Skills & Areas of Study:
  • expertise with phage biology
  • bioinformatics and genomics
  • virology
Salary:
NIH postdoc scale
Location:
Washington University Medical School
660 S. Euclid Ave
Campus Box 8230
St. Louis , MO 63110
US
Contact:
David Wang,