Postdoctoral position is available in the lab of Dr. David Wang at Washington University in St. Louis. RNA bacteriophage have been largely ignored by the scientific community and little is known about their diversity or their impact on the microbiome. Also, there are currently no known bacterial defense mechanisms against RNA viruses. We have discovered 100s of novel RNA bacteriophage in virome studies (e.g. Krishnamurthy et al, PLOS Biology 2016). In addition, we hypothesize that a taxon of viruses commonly found in enteric viromes, the picobirnaviruses, are actually the 3rd known family of RNA bacteriophages ( Krishnamurthy et al, Virology 2018) rather than eukaryotic viruses. The foci of this position include identification of the bacterial hosts, culturing of novel RNA phage, defining the impact of RNA phage on the microbiome, and defining bacterial defense systems against RNA phage.
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