The Department of Medicine/Division of Infectious Diseases seeks a full-time post-doctoral fellow in the laboratory of J. David Beckham, M.D. This laboratory is funded by NIH and VA grants to investigate immune responses to RNA virus infections and mechanisms of immune response in the central nervous system. Research in the lab focuses on applying techniques in virology, immunology, and neuroscience to understand the pathogenesis of RNA virus infections and develop diagnostic and vaccine approaches.
This is a full-time position located at the University of Colorado Anschutz Medical Campus in Aurora, CO. The laboratory is located in the Department of Immunology and Microbiology. The successful candidate will be expected to work independently under the supervision of the principal investigator and research faculty within the laboratory in the design, performance and analysis of experiments. Specific projects and career development opportunities are available in the fields of flavivirus vaccine immunology, flavivirus pathogenesis, neuroimmunology, and Parkinson's disease pathogenesis.
1)Using a flavivirus cloning system in the laboratory, the post-doctoral trainee will develop and analyze immune responses to attenuated flavivirus isolates using various culture and murine models in the laboratory. This work is focused on developing novel live, attenuated vaccines for flavivirus infections.
2) Working with a multidisciplinary group in the laboratory, the successful candidate will utilize several murine models in the laboratory to study immune responses in the central nervous system that contribute to a variety of diseases including encephalitis and neurodegeneration. This portion of the project is focus on using models to study neuroimmunology in the brain.
3) Participate in the multidisciplinary research, education and training of a diverse group of trainees in the laboratory that includes medical and graduate school students, post-graduate trainees, and research assistants.