Categories:
  • Lab Technician
  • Industry
  • Research Scientist
Job Type/Arrangement:
  • Full Time
Description:

We are looking for a highly motivated full-time molecular virologist with a strong background in molecular biology and a strong basic background in Adenovirus/AAV biology. If you are interested, please send us your CV. If this opportunity is not for you, please feel free to share with your network. Thanks!

Responsibilities and Accountabilities 

-Provide leadership role in building and optimizing the design of AAV gene therapy constructs. 

-Contribute to novel AAV capsid design and screening 

-Evaluate novel AAV capsids (tropism, biodistribution, production, etc.) 

-Hands-on, development of two or more of infectivity methods qPCR, ELISA, Western blot, SDS-PAGE test methods desired.

-Partner with disease biology leads to design and execute a delivery strategy

-Responsible for hands-on experimental design, execution, data analysis and reports for AAV vector core pipeline research and development programs. 

-Develop molecular assays to characterize AAV genome integrity, identity, vector variants, residual DNA quantification, as well as in-vitro potency to support product development and manufacturing of gene therapy products. 

-Identification and implementation of operational improvements and novel technologies to improve AAV vector expression and key quality attributes. 

-Participate in project related teams and other internal/external collaborations. 

-Prepare and review technical reports and SOPs to support CMC regulatory activities. 

-In collaboration with Gene Therapy Technical Operations Leadership, develop strategic and operational vision for the organization. 

-Select, develop, and evaluate personnel to ensure the efficient operation of the function and represent the department internally/externally. 

-Work seamlessly with cross functional stakeholders including Process Development, Analytical Development and Translational Research to help advance the AAV vector production portfolio. 

-Ensure the development of robust, well-characterized, high quality and high yielding vector expression system. 

-Ensure that scientific and technical challenges are resolved in a timely manner. 

-Contribute to budget and goal planning. 

-Contribute to a safe, efficient and effective environment with personal accountability. 

About you:  

BS, MS, or Ph.D. degree in Virology, Molecular and Cell Biology or related field. 

-0-2 years of relevant experience with PhD. 

-3-5 years of relevant experience with MS. 

-5-10 years of relevant experience with BS.

AskLife: We offer a competitive total rewards package. 

Are you our next great discovery? 

Education Requirement:
BS, MS, or Ph.D. degree in Virology, Molecular and Cell Biology or related field with at least 1-3 years relevant academic or industry experience.
Years of Experience:
1-10
Required Skills & Areas of Study:
  • synthetic virology
  • areas of research: virology or immunology
  • skills : molecular biology
  • serology
  • experience with animal models
  • flow cytometry
  • molecular virology
  • molecular cell biology
  • • experience in design and optimize dna viral vector (i.e. herpes/adeno) using bac-based cloning technology is desirable. a stro
Location:
Research Triangle Park (RTP)
R&D
20 T. W. Alexander Dr, Suite 110, Research Triangle Park,
Durham , North Carolina 27709
US
Contact:
Lester Suarez, DVM, Ph.D.