We are looking for a highly motivated full-time molecular virologist with a strong background in molecular biology and a strong basic background in Adenovirus/AAV biology. If you are interested, please send us your CV. If this opportunity is not for you, please feel free to share with your network. Thanks!
Responsibilities and Accountabilities
-Provide leadership role in building and optimizing the design of AAV gene therapy constructs.
-Contribute to novel AAV capsid design and screening
-Evaluate novel AAV capsids (tropism, biodistribution, production, etc.)
-Hands-on, development of two or more of infectivity methods qPCR, ELISA, Western blot, SDS-PAGE test methods desired.
-Partner with disease biology leads to design and execute a delivery strategy
-Responsible for hands-on experimental design, execution, data analysis and reports for AAV vector core pipeline research and development programs.
-Develop molecular assays to characterize AAV genome integrity, identity, vector variants, residual DNA quantification, as well as in-vitro potency to support product development and manufacturing of gene therapy products.
-Identification and implementation of operational improvements and novel technologies to improve AAV vector expression and key quality attributes.
-Participate in project related teams and other internal/external collaborations.
-Prepare and review technical reports and SOPs to support CMC regulatory activities.
-In collaboration with Gene Therapy Technical Operations Leadership, develop strategic and operational vision for the organization.
-Select, develop, and evaluate personnel to ensure the efficient operation of the function and represent the department internally/externally.
-Work seamlessly with cross functional stakeholders including Process Development, Analytical Development and Translational Research to help advance the AAV vector production portfolio.
-Ensure the development of robust, well-characterized, high quality and high yielding vector expression system.
-Ensure that scientific and technical challenges are resolved in a timely manner.
-Contribute to budget and goal planning.
-Contribute to a safe, efficient and effective environment with personal accountability.
BS, MS, or Ph.D. degree in Virology, Molecular and Cell Biology or related field.
-0-2 years of relevant experience with PhD.
-3-5 years of relevant experience with MS.
-5-10 years of relevant experience with BS.
AskLife: We offer a competitive total rewards package.
Are you our next great discovery?