Our lab engineers protein-control mechanisms to develop safety switches for RNA viruses in cancer therapy. For example, we have recently engineered drug-induced viral shutoff and signal-specific viral payloads. Two recent publications are:
• Chung HK et al. Tunable and reversible drug control of protein production via a self-excising degron. Nature Chemical Biology 11:713-720. PMID 26214256. (Supported by a NIH R01 grant)
• Chung HK et al. Rewiring aberrant cancer signaling to therapeutic effector release with a synthetic two-component system. Science 2019, 364:eaat6982. PMID 31048459. (Supported by a Damon Runyon Innovation award)
We are now seeking a postdoctoral scientist to study the application of controllable RNA viruses for specific targeting to cancer cells and for delivering immunotherapeutic genes. This is an excellent opportunity for a creative and highly motivated PhD-level scientist to obtain training in cancer virotherapy and contribute to the development of this exciting field. The ideal candidate would have PhD training in a virology-related topic, preferably working with enveloped negative-strand RNA viruses. Experience with mouse models of viral infection or immunological assays are a plus. Excellent communication skills, a strong background in molecular biology, and demonstrated ability to lead a research project are desired.
The candidate can expect to learn cancer biochemistry, synthetic biology, and protein engineering while carrying out an unique research project with high translational potential. The postdoctoral scientist will have the opportunity to join ongoing collaborations with leading labs in cancer biology and immunotherapy. The lab is currently funded by 3 R01 grants and 2 R21 grants. The postdoctoral scientist will have opportunities to apply for fellowships from private research foundations and for internal Stanford-sponsored fellowships if they desire.
Benefits include a minimum postdoctoral salary of $63000 annually, and being part of the vibrant biomedical and bioengineering community at Stanford University, as well as the wider Bay Area academic and biotechnology environment.
Interested candidates may send their CV directly to Dr. Michael Lin at firstname.lastname@example.org.