We study the molecular biology of Kaposi sarcoma herpesvirus (KSHV or HHV8, PMID: 7997879) and Merkel cell polyomavirus (PMID: 18202256 ) discovered by our lab. We also develop new technologies to discover new human cancer viruses. We arefunded through an R35 Outstanding Investigator Award and a new R01, as well as foundational support. Examples of ongoing studies in our lab includes:
KSHV and EBV encoded circular RNAs (circRNAs) Toptan et al. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8737-E8745 PMID: 30150410
E3 ligase regulation of polyomavirus replication Kwun et al. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4040-E4047 PMID: 28461484
Cap-dependent translation regulation by viruses Shuda et al. Proc Natl Acad Sci U S A. 2015 May 12;112(19):5875-82 PMID: 25883264
Proteomic approaches for de novo virus discovery Rigatti et al. mSphere. 2016 Dec 21;1(6). pii: e00334-16 PMID: 28028546 and Dresang et al. BMC Genomics. 2011 Dec 20;12:625 PMID: 22185355
If you are an enthusiastic scientist having demonstrated skills in molecular biology, a strong sense of scientific rigor and an appetite for creative research, then this is an excellent position for you to study viruses in cancer. Successful applicants must have a PhD, MD, or equivalent, together with appropriate publications. Required skills include experience in molecular biology and preferably molecular virology. Although not required, a willingness to learn new techniques and technologies is essential, such as NGS, transcriptomics, immunohistochemistry, RNA biology and animal handling. Pay is based on the current NIH post-doctoral payscale (starting salarly, $50,000 which goes a long way in beautiful PGH) and benefits include University of Pittsburgh health insurance. Exceptional candidates are eligible for the $60,000 Hillman Postdoctoral Fellowship, which includes a $10,000 educational benefit.
For more information, please send your CV and references to: Patrick Moore (firstname.lastname@example.org) and Yuan Chang (email@example.com), University of Pittsburgh Hillman Cancer Center, 5117 Centre Ave. Res Pav 1.9, Pittsburgh, PA USA 15213.