Cancer Virology and Cancer Virus Discovery

University of Pittsburgh

Categories:
  • Post Doctoral Position - Academic
Job Type/Arrangement:
  • Full Time
Description:

We study the molecular biology of Kaposi sarcoma herpesvirus (KSHV or HHV8, PMID: 7997879) and Merkel cell polyomavirus (PMID: 18202256 ) discovered by our lab.  We also develop new technologies to discover new human cancer viruses.  We arefunded through an R35 Outstanding Investigator Award and a new R01, as well as foundational support.  Examples of ongoing studies in our lab includes:

KSHV and EBV encoded circular RNAs (circRNAs)   Toptan et al. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8737-E8745 PMID: 30150410 

E3 ligase regulation of polyomavirus replication Kwun et al. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4040-E4047 PMID: 28461484

Cap-dependent translation regulation by viruses Shuda et al. Proc Natl Acad Sci U S A. 2015 May 12;112(19):5875-82  PMID: 25883264

Proteomic approaches for de novo virus discovery Rigatti et al. mSphere. 2016 Dec 21;1(6). pii: e00334-16 PMID: 28028546 and Dresang et al. BMC Genomics. 2011 Dec 20;12:625 PMID: 22185355

If you are an enthusiastic scientist having demonstrated skills in molecular biology, a strong sense of scientific rigor and an appetite for creative research, then this is an excellent position for you to study viruses in cancer.  Successful applicants must have a PhD, MD, or equivalent, together with appropriate publications.  Required skills include experience in molecular biology and preferably molecular virology.  Although not required, a willingness to learn new techniques and technologies is essential,  such as NGS, transcriptomics, immunohistochemistry, RNA biology and animal handling.   Pay is based on the current NIH post-doctoral payscale (starting salarly, $50,000 which goes a long way in beautiful PGH) and benefits include University of Pittsburgh health insurance.  Exceptional candidates are eligible for the $60,000 Hillman Postdoctoral Fellowship, which includes a $10,000 educational benefit.

For more information, please send your CV and references to:  Patrick Moore (psm9@pitt.edu) and Yuan Chang (yc70@pitt.edu), University of Pittsburgh Hillman Cancer Center, 5117 Centre Ave. Res Pav 1.9, Pittsburgh, PA USA 15213. 


Benefits:
University of Pittsburgh health insurance and postdoctoral benefits package
Education Requirement:
PhD, MD or equivalent
Years of Experience:
0+
Required Skills & Areas of Study:
  • transcriptomics
  • proteomics
  • next gen sequencing
  • molecular biology
  • molecular virology
  • mouse handeling
  • pathogenesis
  • virology
  • genetics
Salary:
$50,000-60,000
Location:
University of Pittsburgh
Cancer Virology Program
5117 Centre Ave, Research Pavilion 1.8
Pittsburgh , PA 15213
US
Contact:
Pat Moore, MD MPH