The Balachandran laboratory is seeking a Postdoctoral Associate to pursue exciting projects centered on the mechanism and role of cell death during influenza A virus (IAV) infections. Specifically, the lab has identified pathways of RIPK3-driven necroptosis and apoptosis triggered in IAV-infected cells, and now looks to explore how these pathways are activated, in which cell types they operate, and how they contribute to immune responses, as well as to pathogenicity. Potential projects will utilize proteomic, CRISPR-based screening, and virological approaches to identify new nodes in these pathways, and to determine their significance in antiviral immune responses in vivo. Please see Nogusa et al. Cell Host Microbe, 2016; Thapa et al. Cell Host Microbe, 2016 for examples of the research carried out in the laboratory. The ideal candidate will hold a Ph.D., with training in IAV Biology, host-pathogen interactions, and/or innate immunology. Prior experience with IAV in cell culture and/or in vivo mouse models of virus pathogenesis will be essential. Familiarity with techniques in cell biological and signal transduction research is an advantage. Please email CV, a cover letter stating research interests, and names of three references to Siddharth.firstname.lastname@example.org.
Fox Chase Cancer Center is a small, comprehensive cancer center that is home to top clinicians and scientists and world-class research facilities. Located in Northeast Philadelphia, the Center is part of a safe, residential neighborhood on the border between Philadelphia and its northern suburbs, with easy access (via car or train) to parks, shopping, dining and all the region's best cultural attractions. Fox Chase offers a rich and supportive training environment, and has consistently ranked in the top 10 places for postdoctoral training in the United States. Moreover, Fox Chase is part of the rich scientific and biotech environment in the Philadelphia region, and many of our former trainees are now employees at these institutions and companies. The support you will receive at Fox Chase goes well beyond the laboratory walls, with training, career development and a generous array of benefits. As a result, Fox Chase has an excellent career placement record in academia and industry, as well as other careers in science.